Home / Biochemistry / Spironolactone for acne Novel Hormonal Therapy may help Stubborn acne
sometimes prescribed off-label for the treatment of hormonal acne
sometimes prescribed off-label for the treatment of hormonal acne

Spironolactone for acne Novel Hormonal Therapy may help Stubborn acne

Spironolactone for acne is a promising treatment for stubborn hormonal acne. Many recent research studies indicate that spironolactone, (a diuretic drug) can be utilized for treating acne caused by hormones, these studies also showed that spironolactone can lead to a reduction of acne by 50% to 100% which is great successful results. In the same context; The Following article will provide you with a comprehensive guide about using this drug to get rid of acne.

What is spironolactone?

Spironolactone is a drug that can only be obtained with a prescription. This medication falls under a category of drugs referred to as (potassium-sparing diuretics) and is employed in the treatment of heart failure, hypertension, and edema. Additionally, it is sometimes prescribed off-label for the treatment of hormonal acne.

spironolactone for acne how does it work

Both males and females produce androgens, which are hormones such as testosterone. Androgens increase the production of oil and sebum, which can exacerbate acne. Spironolactone inhibits the production of these hormones that cause acne and also hinders androgen receptors, ultimately decreasing the formation and occurrence of hormonal acne effectively.

spironolactone for hormonal acne

There are two 2 types of spironolactone medication forms which are: oral and topical drug forms; and each of them has some uses and characteristics as follows:

Oral spironolactone usage

  • Spironolactone which is taken by mouth is a type of medication that helps get rid of excess water in the body and is frequently administered for managing heart failure, hypertension, and edema. It is also commonly recommended as a treatment for acne caused by hormonal imbalances.
  • It hinders the generation and lessens the impact of androgens, such as testosterone, which contribute to the formation of acne.
  • Females can use oral spironolactone safely; while males may experience negative side effects from taking spironolactone orally.

Topical spironolactone usage

  • Applying the topical spironolactone, directly on the skin; has the ability to treat hormonal acne.
  • Safely used for both males and females.
  • Reduces the amount of oils and sebum on the skin and aids in the prevention of blocked pores.

Also Read: best acne treatment for sensitive dry skin depending on nanotechnology and lasers – new study

spironolactone for acne dose

The recommended dosage of oral spironolactone for treating hormonal acne generally ranges from 25 mg to 200 mg. But the appropriate dosage is dependent mainly on some aspects, such as the individual’s health condition and the severity of his acne. So the optimal dose for every patient should be established by the administering healthcare professional.

spironolactone for acne side effects

Potential adverse side effects of spironolactone may include – but are not restricted – to:

  • Abnormal growth of breast tissue in both males and females.
  • The diuretic effect of the drug can lead to a loss of important body electrolytes.
  • There is a possibility of experiencing high levels of potassium, which can cause hypotension and damage to the heart.
  • Digestive system disorders such as diarrhea.
  • Nausea and vomiting.
  • Mild to severe drowsiness.
  • Spironolactone shouldn’t be used during pregnancy or breastfeeding.
  • The drug shouldn’t be used without prescription at all.

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Yasmeen, (Bachelor degree + diploma in biochemistry) + (Master degree from the national institute of laser enhanced science in photobiology and cancer treatment)

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